A Bivariate Genome-Wide Approach to Metabolic Syndrome STAMPEED Consortium
نویسندگان
چکیده
Metabolic Syndrome STAMPEED Consortium Aldi T. Kraja, Dhananjay Vaidya,* James S. Pankow, Mark O. Goodarzi, Themistocles L. Assimes, Iftikhar J. Kullo, Ulla Sovio, Rasika A. Mathias, Yan V. Sun, Nora Franceschini, Devin Absher, Guo Li, Qunyuan Zhang, Mary F. Feitosa, Nicole L. Glazer, Talin Haritunians, Anna-Liisa Hartikainen, Joshua W. Knowles, Kari E. North, Carlos Iribarren, Brian Kral, Lisa Yanek, Paul F. O’Reilly, Mark I. McCarthy, Cashell Jaquish, David J. Couper, Aravinda Chakravarti, Bruce M. Psaty, Lewis C. Becker, Michael A. Province, Eric Boerwinkle, Thomas Quertermous, Leena Palotie, Marjo-Riitta Jarvelin, Diane M. Becker, Sharon L.R. Kardia, Jerome I. Rotter,* Yii-Der Ida Chen,* and Ingrid B. Borecki*
منابع مشابه
A Bivariate Genome-Wide Approach to Metabolic Syndrome
OBJECTIVE The metabolic syndrome (MetS) is defined as concomitant disorders of lipid and glucose metabolism, central obesity, and high blood pressure, with an increased risk of type 2 diabetes and cardiovascular disease. This study tests whether common genetic variants with pleiotropic effects account for some of the correlated architecture among five metabolic phenotypes that define MetS. RESE...
متن کاملطراحی شبکه عصبی مصنوعی برای پیشبینی توأم سندرم متابولیک و شاخص مقاومت به انسولین (HOMA-IR): مطالعه قند و لیپید تهران
Background & Objective: Mixed outcomes arise when, in a multivariate model, response variables measured on different scales such as binary and continuous. In a bivariate modeling, when there are mixed response variables, the common methods in classic statistics have shortcomings. This study aimed at designing an appropriate ANN model for modeling and predicting the bivariate mixed responses i...
متن کاملBivariate Genome-Wide Association Study of Genetically Correlated Neuroimaging Phenotypes from DTI and MRI through a Seemingly Unrelated Regression Model
Large multisite efforts (e.g., the ENIGMA Consortium), have shown that neuroimaging traits including tract integrity (from DTI fractional anisotropy, FA) and subcortical volumes (from T1-weighted scans) are highly heritable and promising phenotypes for discovering genetic variants associated with brain structure. However, genetic correlations (rg) among measures from these different modalities ...
متن کاملGenome-wide computational prediction of miRNAs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) revealed target genes involved in pulmonary vasculature and antiviral innate immunity
The current outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)in China threatened humankind worldwide. The coronaviruses contains the largest RNA genome among all other known RNA viruses, therefore the disease etiology can be understood by analyzing the genome sequence of SARS-CoV-2. In this study, we used an ab-intio based computational tool VMir to scan the complete geno...
متن کاملMetabolic syndrome in a metapopulation of Croatian island isolates.
AIM To investigate the prevalence and factors associated with the metabolic syndrome in 9 isolated populations on Adriatic islands, Croatia, and in the group of immigrants to these islands. METHODS Random samples of 100 inhabitants from each village and 101 immigrants were collected during 2002 and 2003. Bivariate and multivariate methods were used in data analysis. Age, gender, village, diet...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2011